|
KMID : 1007020110090010132
|
|
Korean Soceity of Osteroporosis
2011 Volume.9 No. 1 p.132 ~ p.138
|
|
|
The Study of Bisphosphonate and Postmenopausal Hormone Treatment in Low Bone Mineral Density
|
|
Kim Soo-Ah
Kim A-Ri
Ji Yong-Il
Kim Heung-Yeol
Choi Jong-Soon
Choi Won-Jun
Jung Min-Hyung
Lee Ji-Young
Jung Hyuk
|
|
|
Abstract
|
|
|
Objectives: To evaluate the effect of postmenopausal hormone therapy alone or in combination with bisphosphonate on bone mineral density (BMD) in postmenopausal women.
Methods: One hundred three women diagnosed with low BMD in postmenopausal women were included in this study. All patients were classified into two groups; oarl hormone therpy alone (Group I) or with alendronate (Group II), given for 12 months. Dual energy X-ray absorptiometry was used to measure BMD before and after 12 months of treatment.
Results: In all groups, significant increase in bone density measurements were seen at 12 months of treatment. The BMD of lumbar spine more increased significantly in Group II than Group I.
Conclusions: Postmenopausal hormone therapy is effective in osteopenic and osteoporotic women. However, the combined treatment with hormone therapy and bisphophonate is more effective in postmenopausal women with low BMD.
|
|
|
KEYWORD
|
|
|
Bisphosphonate, Bone mineral density, Hormone therapy, Menopause
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|